Zika virus infection (ZIKV): pathology

Evidence-based neurology checklist on zika virus infection (zikv): pathology: Virology This is an arthropod-borne virus: an arbovirus It is a member of the family Flaviviridae It is neurotropic: it infects neural stem cells Main transmission routes Other possible transmission routes Outbreaks…

Virology

  • This is an arthropod-borne virus: an arbovirus
  • It is a member of the family Flaviviridae
  • It is neurotropic: it infects neural stem cells

Main transmission routes

Other possible transmission routes

Outbreaks

Pathological features

References

  1. de Paula Freitas B, de Oliveira Dias JR, Prazeres J, et al. Ocular findings in infants with microcephaly associated with presumed zika virus congenital infection in Salvador, Brazil. JAMA Ophthalmol 2016; doi: 10.1001/jamaophthalmol.2016.0267 (Epub ahead of print).
  2. Martines RB, Bhatnagar J, de Oliveira Ramos AM, et al. Pathology of congenital Zika syndrome in Brazil: a case series. Lancet 2016; 388:898-904. 
  3. Li H, Saucedo-Cuevas L, Regla-Nava JA, et al. Zika virus infects neural progenitors in the adult mouse brain and alters proliferation. Cell Stem Cell 2016; pii: S1934-5909(16)30252-1 (Epub ahead of print). 
  4. Besnard M, Lastere S, Teissier A, Cao-Lormeau V, Musso D. Evidence of perinatal transmission of Zika virus, French Polynesia, December 2013 and February 2014. Euro Surveill 2014; 19(13). 
  5. Turmel JM, Abgueguen P, Hubert B, et al. Late sexual transmission of Zika virus related to persistence in the semen. Lancet 2016; 387:2501.Roberts DJ, Frosch MP. Zika and histopathology in first trimester infections. Lancet 2016; 388:847-849. 
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