Whipple’s disease: clinical features

Evidence-based neurology checklist on whipple’s disease: clinical features: Movement disorders Oculomasticatory myorrhythmia (OMM) Ataxia Myoclonus Chorea Dystonia Cognitive features Sleep disorders Other central neurological features Peripheral neurological features Ophthalmic features Systemic…

Movement disorders

  • Oculomasticatory myorrhythmia (OMM)
  • Ataxia
  • Myoclonus
  • Chorea
  • Dystonia

Cognitive features

Sleep disorders

Other central neurological features

Peripheral neurological features

Ophthalmic features

Systemic features

Differential diagnosis of CNS Whipple’s disease

References

  1. Panegyres PK, Efis R, Beaman M, Fallon M. Primary Whipple's disease of the brain: characterization of the clinical syndrome and molecular diagnosis. Q J Med 2006; 99:609-623.
  2. Panegyres PK. Diagnosis and management of Whipple's disease of the brain. Pract Neurol 2008; 8:311-317.
  3. Palma JA, Luquin MR, Riverol M, et al. Primary Whipple disease of the CNS presenting with chorea and dystonia: A video case report. Neurol Clin Pract 2014; 4:508-510.
  4. Manini A, Querzola G, Lovati C, Pantoni L. Rapidly progressive dementia and intractable diarrhea: a teaching case report and a systematic review of cognitive impairment in Whipple's disease. Neurol Sci 2022; 43:907-926.
  5. Pessa ME, Baldi A, Gigli GL, Valente M. A case of rapidly progressive dementia: Whipple disease of CNS. Neurol Sci 2018; 39:591-592. 
  6. And 25 more. Subscribe to see the full list

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