Wake-up stroke

Evidence-based neurology checklist on wake-up stroke: Clinical features This occurs in 14-25% of ischemic strokes It has worse outcomes and a higher mortality Magnetic resonance imaging (MRI) Treatment: thrombolysis Treatment: other types Wake-up stroke v daytime unknown time of onset stroke (UTOS)

Clinical features

  • This occurs in 14-25% of ischemic strokes
  • It has worse outcomes and a higher mortality

Magnetic resonance imaging (MRI)

Treatment: thrombolysis

Treatment: other types

Wake-up stroke v daytime unknown time of onset stroke (UTOS)

References

  1. Mackey J, Kleindorfer D, Sucharew H, et al. Population-based study of wake-up strokes. Neurology 2011; 76:1662-1667.
  2. Barreto AD, Martin-Schild S, Hallevi H, et al. Thrombolytic therapy for patients who wake-up with stroke. Stroke 2009; 40:827-832.
  3. Dorado L, Ahmed N, Thomalla G, et al. Intravenous thrombolysis in unknown-onset stroke: results from the safe implementation of treatment in Stroke-International Stroke Thrombolysis Registry. Stroke 2017; 48:720-725. 
  4. Kim BJ, Lee S-H, Shin C-W, et al. Ischemic stroke during sleep: its association with worse early functional outcome. Stroke 2011; 42:1901-1906.
  5. Petkova M, Rodrigo S, Lamy C, et al. MR imaging helps predict tine from symptom onset in patients with acute stroke: implications for patients with unknown onset time. Radiology 2010; 257:782-792.
  6. And 15 more. Subscribe to see the full list

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