VEXAS syndrome
Evidence-based neurology checklist on vexas syndrome: Pathology This is an autoinflammatory disorder It is caused by mutations in the ubiquitin-like modifier-activating enzyme 1 (UBA1) gene The gene is on the X chromosome Epidemiology Systemic features Dermatological features Haematological…
Pathology
- This is an autoinflammatory disorder
- It is caused by mutations in the ubiquitin-like modifier-activating enzyme 1 (UBA1) gene
- The gene is on the X chromosome
Epidemiology
Systemic features
Dermatological features
Haematological features
Respiratory features
Rheumatological features
Ophthalmological features
Gastrointestinal features
Cardiac features
Neurological features
Investigations
Drug treatments
Less effective drug treatments
Non-drug treatments
Acronym
References
- Zhang Y, Dong X, Wang H. VEXAS syndrome - review. Glob Med Genet 2023; 10:133-143.
- Singh A, Chaudhary R. VEXAS syndrome: a newly identified X-Linked hematoinflammatory disorder - A comprehensive overview of its genetic, molecular, inflammatory, and clinical landscape. J Autoimmun 2025; 154:103425.
- Grayson PC, Patel BA, Young NS. VEXAS syndrome. Blood 2021; 137:3591-3594.
