Trigeminal neuralgia (TN): treatment

Evidence-based neurology checklist on trigeminal neuralgia (tn): treatment: First line drug treatments Carbamazepine: level A evidence Oxcarbazepine: level B evidence Second line or add-on drug treatments Insufficient-evidenced drug treatments Acute treatment of relapses: Lidocaine: options Acute…

First line drug treatments

  • Carbamazepine: level A evidence
  • Oxcarbazepine: level B evidence

Second line or add-on drug treatments

Insufficient-evidenced drug treatments

Acute treatment of relapses: Lidocaine: options

Acute treatment of relapses: other options

Microvascular decompression

Gasserian ganglion neuroablative treatments

Treatments of refractory cases

Investigational treatments

References

  1. Gronseth G, Cruccu G, Alksne J, et al. Practice parameter: the diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology and the European Federation of Neurological Societies. Neurology 2008; 71:1183-1190.
  2. Bendtsen L, Zakrzewska JM, Abbott J, et al. European Academy of Neurology guideline on trigeminal neuralgia. Eur J Neurol 2019; 26:831-849.
  3. Attal N, Cruccu G, Baron R, et al. EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision. Eur J Neurol 2010; 17: 1113-1123.
  4. Chong MS, Bahra A, Zakrzewska JM. Guidelines for the management of trigeminal neuralgia. Cleve Clin J Med 2023; 90:355-362.
  5. Uniyal R, Paliwal VK, Kumar N, Malhotra HS, Garg RK, Neyaz Z. Teaching NeuroImages: Amlodipine-responsive trigeminal neuralgia: An alibi for vascular compression theory. Neurology 2017; 89:e20.
  6. And 11 more. Subscribe to see the full list

Related checklists

Loading...