Transient ischaemic attacks (TIA) antiplatelet treatments
Evidence-based neurology checklist on transient ischaemic attacks (tia) antiplatelet treatments: Options for low-risk TIAs (ABCD2 score <4) Aspirin 50-325mg daily Clopidogrel 75mg daily Aspirin 25mg + Dipyridamole 200mg ER bid Options for high-risk TIAs (ABCD2 score ≥4) Options for high-risk TIA…
Options for low-risk TIAs (ABCD2 score <4)
- Aspirin 50-325mg daily
- Clopidogrel 75mg daily
- Aspirin 25mg + Dipyridamole 200mg ER bid
Options for high-risk TIAs (ABCD2 score ≥4)
Options for high-risk TIA with symptomatic intracranial stenosis
Acronym
References
- Fonseca AC, Merwick A, Dennis M, et al. European Stroke Organisation (ESO) guidelines on management of transient ischaemic attack. Eur Stroke J 2021 (Online ahead of print).
- Amin HP, Madsen TE, Bravata DM, et al. Diagnosis, workup, risk reduction of transient ischemic attack in the emergency department setting: a scientific statement from the American Heart Association. Stroke 2023; 54:e109-e121.
- Hao Q, Tampi M, O'Donnell M, Foroutan F, Siemieniuk RA, Guyatt G. Clopidogrel plus aspirin versus aspirin alone for acute minor ischaemic stroke or high risk transient ischaemic attack: systematic review and meta-analysis. BMJ 2018; 363:k5108.
- Prasad K, Siemieniuk R, Hao Q, et al. Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline. BMJ 2018; 363:k5130.
- Johnston SC, Easton JD, Farrant M, et al; Clinical Research Collaboration, Neurological Emergencies Treatment Trials Network, and the POINT Investigators. Clopidogrel and aspirin in acute ischemic stroke and high-risk TIA. N Engl J Med 2018; 379:215-225.
