Transient global amnesia (TGA): clinical features

Evidence-based neurology checklist on transient global amnesia (tga): clinical features: Onset and duration TGA is characterised by an episode of abrupt onset amnesia The duration is usually 1-24 hours but 3% of cases last <1 hour The onset is usually in the morning but not on awakening It is…

Onset and duration

  • TGA is characterised by an episode of abrupt onset amnesia
  • The duration is usually 1-24 hours but 3% of cases last <1 hour
  • The onset is usually in the morning but not on awakening
  • It is recurrent in 6-30% of cases
  • Recurrence can occur multiple times

Amnesia features

Associated neurological features

Associated cardiac features

Other associated features

Exclusion criteria

Diagnostic criteria

Possible predictors of recurrent TGA

References

  1. Kirshner HS. Transient global amnesia: a brief review and update. Curr Neurol Neurosci Rep 2011; 11:578-582.
  2. Quinette P, Guillery-Girard B, Dayan J, et al. What does transient global amnesia really mean? Review of the literature and thorough study of 142 cases. Brain 2006; 129:1640-1658.
  3. Brigo F, Tezzon F, Nardone R. "Once again she forgets everything!": a patient with four episodes of transient global amnesia within less than 5 years. Acta Neurol Belg 2018; 118:319-320.
  4. Piffer S, Nannoni S, Maulucci F, et al. Transient global amnesia with unexpected clinical and radiological findings: A case series and systematic review. J Neurol Sci 2022; 441:120349.
  5. Nagamine T. Transient global amnesia with transient anosmia: a curious case suggestive of middle cerebral artery occlusion. J Integr Neurosci 2022; 21:103.
  6. And 15 more. Subscribe to see the full list

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