Tick borne encephalitis virus (TBEV)

Evidence-based neurology checklist on tick borne encephalitis virus (tbev): Biology This is a flavivirus The transmission is by Ixodes ricinus, persulcatus and ovatus ticks It is transmitted through unpasteurized cow, goat, or sheep dairy products It is maintained in rodents The infection is…

Biology

  • This is a flavivirus
  • The transmission is by Ixodes ricinus, persulcatus and ovatus ticks
  • It is transmitted through unpasteurized cow, goat, or sheep dairy products
  • It is maintained in rodents
  • The infection is highest between April and November

Biphasic presentation

Clinical phenotypes

Clinical features

Cerebrospinal fluid (CSF) analysis

Blood investigations

Indications for vaccination

Treatment

References

  1. Taba P, Schmutzhard E, Forsberg P, et al. EAN consensus review on prevention, diagnosis and management of tick-borne encephalitis. Eur J Neurol 2017; 24:1214-e61. 
  2. Bogovic P, Strle F. Tick-borne encephalitis: a review of epidemiology, clinical characteristics, and management. World J Clin Cases 2015; 3:430-441.
  3. Zavadska D, Anca I, André F, et al. Recommendations for tick-borne encephalitis vaccination from the Central European Vaccination Awareness Group (CEVAG). Hum Vaccin Immunother 2013; 9:362-374. 
  4. Logina I, Krumina A, Karelis G, et al. Clinical features of double infection with tick-borne encephalitis and Lyme borreliosis transmitted by tick bite. JNNP 2006; 77:1350-1353.

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