Thalamic aphasia syndrome

Evidence-based neurology checklist on thalamic aphasia syndrome: Pathology This is caused by disconnection of cortical language areas from the thalamic nuclei The lesion is usually in the dominant thalamus or supplementary motor region (SMR) It is worse with left sided lesions Language impairments…

Pathology

  • This is caused by disconnection of cortical language areas from the thalamic nuclei 
  • The lesion is usually in the dominant thalamus or supplementary motor region (SMR)
  • It is worse with left sided lesions

Language impairments

Clinical features

Preserved language functions

References

  1. Jonas S. The thalamus and aphasia, including transcortical aphasia: a review. J Commun Disord 1982; 15:31-41.
  2. Afzal U, Farooq MU. Teaching neuroimages: thalamic aphasia syndrome. Neurology 2013; 81:e177. 
  3. Gorelick PB, Hier DB, Benevento L, Levitt S, Tan W. Aphasia after left thalamic infarction. Arch Neurol 1984; 41:1296-1298.
  4. Fritsch M, Rangus I, Nolte CH. Thalamic aphasia: a review. Curr Neurol Neurosci Rep 2022; 22:855-865.
  5. Rangus I, Fritsch M, Endres M, Udke B, Nolte CH. Frequency and phenotype of thalamic aphasia. J Neurol 2021 (Online ahead of print).

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