Superficial siderosis (SS): investigations

Evidence-based neurology checklist on superficial siderosis (ss): investigations: Magnetic resonance imaging (MRI): location of diffuse hypointensities Surface of cerebellum, brain stem, and spinal cord Along cerebellar folia and vermis Interhemispheric Sylvian fissure Along vestibulochochlear…

Magnetic resonance imaging (MRI): location of diffuse hypointensities

  • Surface of cerebellum, brain stem, and spinal cord
  • Along cerebellar folia and vermis
  • Interhemispheric
  • Sylvian fissure
  • Along vestibulochochlear nerve

Magnetic resonance imaging (MRI): other features

Cerebrospinal fluid (CSF) analysis

References

  1. Messori A, Bella PD, Herber N, Logullo F, Ruggiero M, Salvolini U. The importance of suspecting superficial siderosis of the central nervous system in clinical practice. JNNP 2004; 75:188-190.
  2. Kumar N. Superficial siderosis: associations and therapeutic implications. Arch Neurol 2007; 64:491-496.
  3. Kumar N, Bledsoe JM, Davis DH. Intracranial fluid filled collection and superficial siderosis. JNNP 2007; 78:652-653.
  4. Charidimou A, Boulouis G, Xiong L, et al. Cortical superficial siderosis and first-ever cerebral hemorrhage in cerebral amyloid angiopathy. Neurology 2017; 88:1607-1614.
  5. Moulin S, Casolla B, Kuchcinski G, et al. Cortical superficial siderosis: a prospective observational cohort study. Neurology 2018; 91:e132-e138.
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