Stroke on antiplatelet therapy: management
Evidence-based neurology checklist on stroke on antiplatelet therapy: management: Use higher loading doses Higher doses of Aspirin increase bleeding risk The safety of higher doses of Clopidogrel is not confirmed The effectiveness of this strategy is not confirmed Switching between Aspirin and…
Use higher loading doses
- Higher doses of Aspirin increase bleeding risk
- The safety of higher doses of Clopidogrel is not confirmed
- The effectiveness of this strategy is not confirmed
Switching between Aspirin and Clopidogrel
Switching to alternative drugs
Combination treatments
Benefits and risks of switching and combination therapies
Synonym
References
- Michos ED, Ardehali R, Blumenthal RS, Lange RA, Ardehali H. Aspirin and clopidogrel resistance. Mayo Clin Proc 2006; 81:518-526.
- Uchiyama S. Clopidogrel resistance: identifying and overcoming a barrier to effective antiplatelet treatment. Cardiovasc Ther 2011; 29:e100-e111.
- Topçuoglu MA, Arsava EM, Ay H. Antiplatelet resistance in stroke. Expert Rev Neurother 2011; 11:251-263.
- Niu PP, Guo ZN, Jin H, Xing YQ, Yang Y. Antiplatelet regimens in the long-term secondary prevention of transient ischaemic attack and ischaemic stroke: an updated network meta-analysis. BMJ Open 2016; 6:e009013.
- Feher G, Feher A, Pusch G, et al. Clinical importance of aspirin and clopidogrel resistance. World J Cardiol 2010; 2:171-186.
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