SMART syndrome: clinical features

Evidence-based neurology checklist on smart syndrome: clinical features: Definition This is stroke-like migraine attacks after radiotherapy (SMART) It is a late complication of cranial radiation Recommended new terminology Diagnostic criteria Clinical features Course Differential diagnosis:…

Definition

  • This is stroke-like migraine attacks after radiotherapy (SMART)
  • It is a late complication of cranial radiation

Recommended new terminology

Diagnostic criteria

Clinical features

Course

Differential diagnosis: vascular

Differential diagnosis: others

References

  1. Lim SY, Brooke J, Dineen R, O'Donoghue M. Stroke-like migraine attack after cranial radiation therapy: the SMART syndrome. Pract Neurol 2016; 16:406-408. 
  2. Kerklaan JP, Lycklama á Nijeholt GJ, Wiggenraad RG, Berghuis B, Postma TJ, Taphoorn MJ. SMART syndrome: a late reversible complication after radiation therapy for brain tumours. J Neurol 2011; 258:1098-1104.
  3. Ramanathan RS, Sreedher G, Malhotra K, et al. Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome. Ann Indian Acad Neurol 2016; 19:399-401. 
  4. Ferlazzo E, Ascoli M, Gasparini S, et al. Seizures with Migraine-like Attacks after Radiation Therapy (SMART): A new meaning of an old acronym. Seizure 2018; 60:94-95.
  5. Fan EP, Heiber G, Gerard EE, Schuele S. Stroke-like migraine attacks after radiation therapy: a misnomer? Epilepsia 2018; 59:259-268. 
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