Rasmussen’s encephalopathy (RE): management
Evidence-based neurology checklist on rasmussen’s encephalopathy (re): management: Magnetic resonance imaging (MRI): features Hyperintensities: these are in the grey-white matter and the head of caudate Unilateral hemispheric cortical atrophy Contralateral atrophy: this develops slowly…
Magnetic resonance imaging (MRI): features
- Hyperintensities: these are in the grey-white matter and the head of caudate
- Unilateral hemispheric cortical atrophy
- Contralateral atrophy: this develops slowly
Electroencephalogram (EEG): features
Potential immune treatments
Epilepsy treatments
Other treatments
References
- Bien CG, Granata T, Antozzi C, et al. Pathogenesis, diagnosis and treatment of Rasmussen encephalitis. Brain 2005; 128:454-471.
- Varadkar S, Bien CG, Kruse CA, et al. Rasmussen's encephalitis: clinical features, pathophysiology, and treatment advances. Lancet Neurol 2014; 13:195-205.
- Bittner S, Simon OJ, Gobel K, Bien CG, Meuth SG, Wiendl H. Rasmussen encephalitis treated with Natalizumab. Neurology 2013; 81:395-397.
- Pellegrin S, Baldeweg T, Pujar S, et al. Immunomodulation with azathioprine therapy in rasmussen syndrome: a multimodal evaluation. Neurology 2021; 96:e267-e279.
- Lagarde S, Villeneuve N, Trébuchon A, et al. Anti-tumor necrosis factor alpha therapy (adalimumab) in Rasmussen’s encephalitis: an open pilot study. Epilepsia 2016; 57:956-966.
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