Radiation induced non-vascular neurological disorders
Evidence-based neurology checklist on radiation induced non-vascular neurological disorders: Post-radiotherapy pseudoprogression This is the development of new areas of contrast enhancement soon after chemoradiotherapy It especially occurs with 1p/19q intact oligodendrogliomas and mixed…
Post-radiotherapy pseudoprogression
- This is the development of new areas of contrast enhancement soon after chemoradiotherapy
- It especially occurs with 1p/19q intact oligodendrogliomas and mixed oligoastrocytomas
- Increased cerebral blood flow may distinguish it from real progression
- It may respond to Bevacizumab
Radiation-induced myelopathy
Radiation-induced imaging disorders
Radiation-induced tumours
Radiation-induced movement disorders
Other radiation-induced central neurological disorders
References
- Lin AL, White M, Miller-Thomas MM, et al. Molecular and histologic characteristics of pseudoprogression in diffuse gliomas. J Neurooncol 2016; 130:529-533.
- Lin AL, Liu J, Evans J, et al. Codeletions at 1p and 19q predict a lower risk of pseudoprogression in oligodendrogliomas and mixed oligoastrocytomas. Neuro Oncol 2014; 16:123-130.
- Calmon R, Puget S, Varlet P, et al. Cerebral blood flow changes after radiation therapy identifies pseudoprogression in diffuse intrinsic pontine gliomas. Neuro Oncol 2018; 20:994-1002.
- Nguyen TK, Perry J, Sundaram ANE, et al. Rescue bevacizumab following symptomatic pseudoprogression of a tectal glioma post-radiotherapy: a case report and review of the literature. J Neurooncol 2019; 143:475-481.
- Gibbs IC, Patil C, Gerszten PC, Adler JR Jr, Burton SA. Delayed radiation-induced myelopathy after spinal radiosurgery. Neurosurgery 2009; 64(2 Suppl):A67-A72.
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