Pure autonomic failure (PAF)
Evidence-based neurology checklist on pure autonomic failure (paf): Pathology This is postganglionic It is a synucleinopathy There are Lewy body deposits in the autonomic ganglia and nerve Phenoconversion to α-synucleinopathy disorders Synonym
Pathology
- This is postganglionic
- It is a synucleinopathy
- There are Lewy body deposits in the autonomic ganglia and nerve
Phenoconversion to α-synucleinopathy disorders
Synonym
References
- Sandroni P, Low PA. Other autoimmune neuropathies associated with ganglionic antibody. Auton Neurosci 2009; 146:13-17.
- Coon EA, Singer W, Low PA. Pure autonomic failure. Mayo Clin Proc 2019; 94:2087-2098.
- Autonomic failure in neurodegenerative disorders. Kaufmann H, Biaggioni I.Semin Neurol 2003; 23:351-63.
- Virameteekul S, Bonini I, Campese N, et al. Phenoconversion in pure autonomic failure: a systematic review and meta-analysis. JAMA Neurol 2026; 83:616-624.
