Progressive myoclonic epilepsy (PME): clinical features
Evidence-based neurology checklist on progressive myoclonic epilepsy (pme): clinical features: Myoclonic seizures These manifest as cortical reflex myoclonus They are stimulus sensitive: to light, sound, and touch They are fragmentary and multifocal They especially occur in the face and distal…
Myoclonic seizures
- These manifest as cortical reflex myoclonus
- They are stimulus sensitive: to light, sound, and touch
- They are fragmentary and multifocal
- They especially occur in the face and distal limbs
- They may present as massive bilateral proximal myoclonus
Other seizure types: in Lafora body disease
Cerebellar features
Ophthalmic features
Other neurological features
Other features
References
- Cameron JM, Ellis CA, Berkovic SF, et al. ILAE genetics literacy series: progressive myoclonus epilepsies. Epileptic Disord 2023 (Online ahead of print).
- Franceschetti S, Michelucci R, Canafoglia L, et al. Progressive myoclonic epilepsies: definitive and still undetermined causes. Neurology 2014; 82:405-411.
