Primary hyperparathyroidism

Evidence-based neurology checklist on primary hyperparathyroidism: Causes Hyperthyroid adenoma Multiple endocrine neoplasia (MEN) Hyperparathyroid-jaw tumour syndrome Central neurological features Peripheral neurological features Psychiatric features Constitutional features Systemic features…

Causes

  • Hyperthyroid adenoma
  • Multiple endocrine neoplasia (MEN)
  • Hyperparathyroid-jaw tumour syndrome

Central neurological features

Peripheral neurological features

Psychiatric features

Constitutional features

Systemic features

Biochemical features

Differential diagnosis

References

  1. Walker MD, Silverberg SJ. Primary hyperparathyroidism. Nat Rev Endocrinol 2018; 14:115-125. 
  2. Patten BM, Pages M. Severe neurological disease associated with hyperparathyroidism. Ann Neurol 1984; 15:453-456.
  3. Roy M, Sahana PK, Sengupta N, Das C, Dasgupta R. An unusual case of episodic quadriparesis. Indian J Endocrinol Metab 2013; 17(Suppl 1):S234-S236.
  4. Cagney D, Razzaq Z, Majeed M, O'Leary DP, Redmond HP. Primary hyperparathyroidism causing posterior reversible encephalopathy syndrome: a case report. Ann R Coll Surg Engl 2021; 103:e341-e344.
  5. Pal R, Dutta A, Agrawal K, Jain N, Dutta P, Bhansali A, Behera A, Bhadada SK. Primary hyperparathyroidism presenting as posterior reversible encephalopathy syndrome: a report of two cases. J Clin Res Pediatr Endocrinol 2020; 12:432-438.
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