Pregnancy and Parkinson’s disease (PD)

Evidence-based neurology checklist on pregnancy and parkinson’s disease (pd): Effect of pregnancy on Parkinson’s disease (PD) Most pregnancies are completed without complications There are case reports of PD worsening in pregnancy PD is not associated with increased foetal or birth complications…

Effect of pregnancy on Parkinson’s disease (PD)

  • Most pregnancies are completed without complications
  • There are case reports of PD worsening in pregnancy
  • PD is not associated with increased foetal or birth complications
  • The spontaneous abortion rate is 8-9%
  • Depression is the most frequent post-partum complication

Safety of PD drugs in pregnancy

Management of PD in pregnancy and breastfeeding

Acronym

References

  1. Shulman LM, Minagar A, Weiner WJ. The effect of pregnancy in Parkinson's disease. Mov Disord 2000; 15:132-135.
  2. Seier M, Hiller A. Parkinson's disease and pregnancy: an updated review. Parkinsonism Relat Disord 2017; 40:11-17.
  3. Lamichhane D, Narayanan NS, Gonzalez-Alegre P. Two cases of pregnancy in Parkinson's disease. Parkinsonism Relat Disord 2014; 20:239-240. 
  4. Young C, Phillips R, Ebenezer L, Zutt R, Peall KJ. Management of Parkinson's disease during pregnancy: literature review and multidisciplinary input. Mov Disord Clin Pract 2020; 7:419-430.
  5. Olivola S, Xodo S, Olivola E, Cecchini F, Londero AP, Driul L. Parkinson's disease in pregnancy: a case report and review of the literature. Front Neurol 2020; 10:1349. 
  6. And 2 more. Subscribe to see the full list

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