Pregnancy and haemangioblastoma
Evidence-based neurology checklist on pregnancy and haemangioblastoma: Manifestations in pregnancy Enlargement of cerebellar lesions may result in hydrocephalus Associated pheochromocytoma may result in foetal loss Spinal lesions present with back pain and paraesthesias in pregnancy Cervical…
Manifestations in pregnancy
- Enlargement of cerebellar lesions may result in hydrocephalus
- Associated pheochromocytoma may result in foetal loss
- Spinal lesions present with back pain and paraesthesias in pregnancy
- Cervical spinal lesions may present with dysautonomia
Risk of enlargement in pregnancy
Treatment
Acronyms
References
- Capone F, Profice P, Pilato F, Zollino M, Colosimo C, Di Lazzaro V. Spinal hemangioblastoma presenting with low back pain in pregnancy. Spine J 2013; 13:e27-e29.
- da Mota Silveira Rodrigues A, Simões Fernandes F, Farage L, et al. Pregnancy-induced growth of a spinal hemangioblastoma: presumed mechanisms and their implications for therapeutic approaches. Int J Womens Health 2018; 10:325-328.
- Laviv Y, Wang JL, Anderson MP, Kasper EM. Accelerated growth of hemangioblastoma in pregnancy: the role of proangiogenic factors and upregulation of hypoxia-inducible factor (HIF) in a non-oxygen-dependent pathway. Neurosurg Rev 2019; 42:209-226.
- Frantzen C, Kruizinga RC, van Asselt SJ, et al. Pregnancy-related hemangioblastoma progression and complications in von Hippel-Lindau disease. Neurology 2012; 79:793-796.
- Ma XJ, Zhang GB, Guo TX, et al. Management and outcomes of pregnant patients with central nervous system hemangioblastoma. J Clin Neurosci 2018; 57:126-130.
