Pregnancy and cerebral aneurysms

Evidence-based neurology checklist on pregnancy and cerebral aneurysms: Pathogenesis of aneurysms in pregnancy Pregnancy increases the risk of aneurysm development and rupture This is due to the haemodynamic changes in pregnancy The high plasma volume in pregnancy may delay the onset of symptoms…

Pathogenesis of aneurysms in pregnancy

  • Pregnancy increases the risk of aneurysm development and rupture
  • This is due to the haemodynamic changes in pregnancy
  • The high plasma volume in pregnancy may delay the onset of symptoms of aneurysm rupture
  • Features of rupture may be wrongly attributed to eclampsia
  • Rupture may compromise placental blood flow and cause foetal distress

Aneurysm rupture risk in pregnancy

Features predicting high risk of aneurysm rupture

Management of pregnancy with an aneurysm

Management of aneurysms in pregnancy

Outcomes of pregnancies with aneurysms

Predictors of maternal mortality

References

  1. Barbarite E, Hussain S, Dellarole A, Elhammady MS, Peterson E. The management of intracranial aneurysms during pregnancy: a systematic review. Turk Neurosurg 2016; 26:465-474.
  2. Pankaja S, Choudhary V, Rashid M. Ruptured intracranial aneurysm in pregnancy: a case report. BMJ Case Rep 2009; pii: bcr07.2008.0437. 
  3. Roman H, Descargues G, Lopes M, et al. Subarachnoid hemorrhage due to cerebral aneurysmal rupture during pregnancy. Acta Obstet Gynecol Scand 2004; 83:330-334.
  4. Tanaka H, Katsuragi S, Tanaka K, et al. Impact of pregnancy on the size of small cerebral aneurysm. J Matern Fetal Neonatal Med 2017; 30:2759-2762. 
  5. Davie CA, O'Brien P. Stroke and pregnancy. JNNP 2008; 79:240-245. 
  6. And 4 more. Subscribe to see the full list

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