Pineal gland calcification (PGC)

Evidence-based neurology checklist on pineal gland calcification (pgc): Physiological causes The pineal is calcified in 10% of normal children aged 11-14 years It is rare to be calcified under the age of 6.5 years Calcification under the age of 9 years is usually pathological Calcification is more…

Physiological causes

  • The pineal is calcified in 10% of normal children aged 11-14 years
  • It is rare to be calcified under the age of 6.5 years
  • Calcification under the age of 9 years is usually pathological
  • Calcification is more frequent with older age, male sex and White ethnicity

Malignant causes

Other causes and risk factors

References

  1. Gaillard F, Jones J. Masses of the pineal region: clinical presentation and radiographic features. Postgrad Med J 2010; 86:597-607.
  2. Kıroğlu Y, Çallı C, Karabulut N,  Öncel C. Intracranial calcifications on CT. Diagn Interv Radiol 2010; 16:263-269.
  3. Belay DG, Worku MG. Prevalence of pineal gland calcification: systematic review and meta-analysis. Syst Rev 2023; 12:32.
  4. Ozlece HK, Akyuz O, Ilik F, et al. Is there a correlation between the pineal gland calcification and migraine? Eur Rev Med Pharmacol Sci 2015; 19:3861-3864.
  5. Sandyk R. Pineal and habenula calcification in schizophrenia. Int J Neurosci 1992; 67:19-30.
  6. And 1 more. Subscribe to see the full list

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