Pathological laughter

Evidence-based neurology checklist on pathological laughter: Clinical features This is involuntary laughter It occurs in response to non-specific stimuli There is no corresponding change in mood Neoplastic causes Neurological causes Treatment

Clinical features

  • This is involuntary laughter
  • It occurs in response to non-specific stimuli
  • There is no corresponding change in mood

Neoplastic causes

Neurological causes

Treatment

References

  1. Wild B, Rodden FA, Grodd W, Ruch W. Neural correlates of laughter and humour. Brain 2003; 126:2121-2138.
  2. Famularo G, Corsi F, Minisola G, De Simone C, Nicotra GC. Cerebellar tumour presenting as pathological laughter and gelastic syncope. Eur J Neurol 2007; 14:940-943.
  3. Rodriguez Campello A, Padcual Calvet J, Pou Serradell A. Crazy laughter: first manifestation of a pontine tumour. Neurologia 2003; 18:225-228.
  4. Tsutsumi S, Hatashita S, Kadota Y, Abe K, Ueno H. Tentorial meningioma associated with pathological laughter-case report. Neurol Med Chir (Tokyo) 2000; 40:272-274.
  5. Ceccaldi M, Donnet A, Grisoli F, Poncet M. Prodromic fit of laughter and prerolandic tumour. Rev Neurol (Paris) 1995; 151:206-208.
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