Patent foramen ovale (PFO) and migraine
Evidence-based neurology checklist on patent foramen ovale (pfo) and migraine: Epidemiology of PFO and migraine PFO is present in 30% of the population There is probably no association between migraine and isolated PFO Migraine is associated with PFO if accompanied by atrial septal aneurysm (ASA)…
Epidemiology of PFO and migraine
- PFO is present in 30% of the population
- There is probably no association between migraine and isolated PFO
- Migraine is associated with PFO if accompanied by atrial septal aneurysm (ASA)
- There is possibly an increased frequency of PFO in migraine with aura
- Migraineurs may have larger PFOs than non-migraineurs
Drug treatment
Preventive measures
Benefit of PFO closure
Indications for PFO closure
Complications of PFO closure
References
- Anzola GP, Mazzucco S. The patent foramen ovale-migraine connection: a new perspective to demonstrate a casual relation. Neurol Sci 2008; 29:S15-S18.
- Diener HC, Kurth T, Dodick D. Patent foramen ovale. Curr Pain Headache Rev 2007; 11:236-240.
- Dowson A, Mullen MJ, Peatfield R, et al. Migraine Intervention with STARFlex Technology (MIST) trial: a prospective, multicenter, double-blind sham-controlled trial to evaluate the effectiveness of patent foramen ovale closure with STARFlex septal repair implant to resolve refractory migraine headache. Circulation 2008; 117:1397-1404.
- D'Amico D, Usai S, Caputi L, Bussone G. Does closure of a patent foramen ovals have a role in the treatment of migraine with aura? Neurol Sci 2008; 29:S23-S27.
- Tepper SJ, Cleves C, Taylor FR. Patent foramen ovale and migraine: association, causation and implications of clinical trials. Curr Pain Headache Rev 2009; 13:221-226.
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