Paroxysmal hypothermia: causes
Evidence-based neurology checklist on paroxysmal hypothermia: causes: Major causes: Shapiro syndrome This is associated with agenesis of the corpus callosum It may be linked with genetic mutations: SCN, KCNQ, KCNA, CHRNA, GABRB Hypoglycaemia has been reported Holoprosencephaly has been reported…
Major causes: Shapiro syndrome
- This is associated with agenesis of the corpus callosum
- It may be linked with genetic mutations: SCN, KCNQ, KCNA, CHRNA, GABRB
- Hypoglycaemia has been reported
- Holoprosencephaly has been reported
Major causes: others
Vascular causes
Infective causes
Iatrogenic causes
Spontaneous or idiopathic: possible mechanisms
Other causes
References
- Goh Y, Lee XY, Chin AXY, Jing M, Makmur A, Quek AML. Shapiro syndrome: a cause of episodic hyperhidrosis, hypothermia and altered mental status. QJM 2023 (Online ahead of print).
- Ren L, Gang X, Yang S, Sun M, Wang G. A new perspective of hypothalamic disease: Shapiro's syndrome. Front Neurol 2022; 13:911332.
- Lewis C, Freeman N, Gupta N. Hypoglycemia as a manifestation of Shapiro syndrome. Cureus 2022; 14:e23120.
- Evers Smith CM, Creed E. Case report of dysmorphic physical findings in male with Shapiro syndrome. Cureus 2022; 14:e26064.
- Hemelsoet DM, De Bleecker JL. Post-traumatic spontaneous recurrent hypothermia: a variant of Shapiro's syndrome. Eur J Neurol 2007; 14:224-227.
- And 6 more. Subscribe to see the full list
