Paroxysmal dysarthria ataxia (PDA)

Evidence-based neurology checklist on paroxysmal dysarthria ataxia (pda): Pathology Secondary types are related to lesions around the red nucleus It is caused by dysfunction of the cerebellothalamocortical pathway Classification Variants Secondary causes Onset features Clinical pattern Clinical…

Pathology

  • Secondary types are related to lesions around the red nucleus
  • It is caused by dysfunction of the cerebellothalamocortical pathway

Classification

Variants

Secondary causes

Onset features

Clinical pattern

Clinical features

Magnetic resonance imaging (MRI) brain

Other investigations

Treatment of secondary types

References

  1. Marcel C, Anheim M, Flamand-Rouvière C, et al. Symptomatic paroxysmal dysarthria-ataxia in demyelinating diseases. J Neurol 2010; 257:1369-1372.
  2. Li Y, Zeng C, Luo T. Paroxysmal dysarthria and ataxia in multiple sclerosis and corresponding magnetic resonance imaging findings. J Neurol 2011; 258:273-276.
  3. Matsui M, Tomimoto H, Sano K, Hashikawa K, Fukuyama H, Shibasaki H. Paroxysmal dysarthria and ataxia after midbrain infarction. Neurology 2004; 63:345-347. 
  4. Maramattom BV. Paroxysmal dysarthria ataxia-tremor-blepharospasm syndrome in Bickerstaff brainstem encephalitis; a variant of paroxysmal dysarthria ataxia syndrome. Neurol India 2022; 70:437-438.
  5. Ferrante E, Marazzi MR, Trimboli M, Dalla Costa D, Erminio C, Nobili L. Brainstem lesion causing paroxysmal ataxia, dysarthria, diplopia and hemifacial spasm (PADDHS). Epileptic Disord 2019; 21:389-390.
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