Pallido-pyramidal syndromes (PPS)

Evidence-based neurology checklist on pallido-pyramidal syndromes (pps): Clinical features - Davison’s triad Dystonia Spasticity Progressive parkinsonism Types Infantile PPS types (onset <2years) Juvenile PPS types Adult PPS types Other PPS types Arguments against the existence of PPS Synonym…

Clinical features - Davison’s triad

  • Dystonia
  • Spasticity
  • Progressive parkinsonism

Types

Infantile PPS types (onset <2years)

Juvenile PPS types

Adult PPS types

Other PPS types

Arguments against the existence of PPS

Synonym

Acronym

References

  1. Kruer MC, Salih MA, Mooney C, et al. C19orf12 mutation leads to a pallido-pyramidal syndrome. Gene 2014; 537:352-356. 
  2. Kara E, Hardy J, Houlden H. The pallidopyramidal syndromes: nosology, aetiology and pathogenesis. Curr Opin Neurol 2013; 26:381-394.
  3. Paisan-Ruiz C, Bhatia KP, Li A, et al. Characterization of PLA2G6 as a locus for dystonia-parkinsonism. Ann Neurol 2009; 65:19-23. 
  4. Di Fonzo A, Dekker MC, Montagna P, et al. FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome. Neurology 2009; 72:240-245. 
  5. Tranchant C, Koob M, Anheim M. Parkinsonian-pyramidal syndromes: a systematic review. Parkinsonism Relat Disord 2017; 39:4-16. 
  6. And 2 more. Subscribe to see the full list

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