Ohtahara syndrome: management
Evidence-based neurology checklist on ohtahara syndrome: management: Electroencephalogram (EEG) This shows a suppression burst pattern There are high amplitude spikes and polyspikes These alternate with periods of electric suppression The abnormalities persist in sleep There is hypsarrhythmia when…
Electroencephalogram (EEG)
- This shows a suppression burst pattern
- There are high amplitude spikes and polyspikes
- These alternate with periods of electric suppression
- The abnormalities persist in sleep
- There is hypsarrhythmia when West syndrome sets in
Anti-epileptic drugs (AEDs)
Other treatments
References
- Beal JC, Cherian K, Moshe SL. Early-onset epileptic encephalopathies: Ohtahara syndrome and early myoclonic encephalopathy. Pediatr Neurol 2012; 47:317-323.
- Fullston T, Brueton L, Willis T, et al. Ohtahara syndrome in a family with an ARX protein truncation mutation (c.81C>G/p.Y27X). Eur J Hum Genet 2010; 18:157-162.
- Kural Z, Ozer AF. Epileptic encephalopathies in adults and childhood. Epilepsy Res Treat 2012; 2012:205131.
- Wilmshurst JM, Gaillard WD, Vinayan KP, et al. Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics. Epilepsia 2015; 56:1185-1197.
