Non-systemic vasculitic peripheral neuropathy (PN)

Evidence-based neurology checklist on non-systemic vasculitic peripheral neuropathy (pn): Clinical features This accounts for 10% of vasculitic neuropathy The average onset age is 60 years Women account for 60% of cases The features are similar to systemic vasculitis but the prognosis is better…

Clinical features

  • This accounts for 10% of vasculitic neuropathy
  • The average onset age is 60 years
  • Women account for 60% of cases
  • The features are similar to systemic vasculitis but the prognosis is better
  • Relapses may occur: especially if only steroid treatment was administered

Investigations

First line treatment

Maintenance treatment

Treatment of refractory cases

Treatments of unproven benefit

Monitoring indices

References

  1. Vrancken AFJE, Hughes RAC, Said G, Wokke JHJ, Notermans NC. Immunosuppressive treatment for non-systemic vasculitic neuropathy. Cochrane Database of Systematic Reviews 2007; Issue 1. Art. No.: CD006050.
  2. Matthew L, Talbot K, Love S, Puvanarajah S, Donaghy M. Treatment of vasculitic peripheral neuropathy: a retrospective analysis of outcome. Q J Med 2007; 100:41-51.
  3. Collins MP, Dyck JB, Gronseth GS, et al. Peripheral Nerve Society guideline on the classification, diagnosis, investigation, and immunosuppressive therapy of non-systemic vasculitic neuropathy: executive summary. J Peripher Nerv Syst 2010; 15:176-184.

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