Non-convulsive status epilepticus (NCSE): treatment

Evidence-based neurology checklist on non-convulsive status epilepticus (ncse): treatment: First line: intravenous benzodiazepines Lorazepam 0.5-1mg doses; the maximum dose is 10mg Midazolam 1mg doses; the maximum dose is 0.1mg/kg Second line Third line Rescue therapy for refractory NCSE

First line: intravenous benzodiazepines

  • Lorazepam 0.5-1mg doses; the maximum dose is 10mg
  • Midazolam 1mg doses; the maximum dose is 0.1mg/kg

Second line

Third line

Rescue therapy for refractory NCSE

References

  1. Sutter R, Rüegg S, Kaplan PW. Epidemiology, diagnosis, and management of nonconvulsive status epilepticus: opening Pandora's box. Neurol Clin Pract 2012; 2:275-286.
  2. Kinney MO, Craig JJ, Kaplan PW. Non-convulsive status epilepticus: mimics and chameleons. Pract Neurol 2018; 18:291-305.
  3. Holtkamp M, Meierkord H. Nonconvulsive status epilepticus: a diagnostic and therapeutic challenge in the intensive care setting. Ther Adv Neurol Disord 2011; 4:169-181.

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