New daily persistent headache (NDPH)

Evidence-based neurology checklist on new daily persistent headache (ndph): Clinical features This is usually a sudden thunderclap onset Subjects have an accurate recollection of its onset There is no preceding migraine or tension type headache (TTH) Some patients may have typical migraine…

Clinical features

  • This is usually a sudden thunderclap onset
  • Subjects have an accurate recollection of its onset
  • There is no preceding migraine or tension type headache (TTH)
  • Some patients may have typical migraine features
  • The headache is worse in the Trendelenburg (head down) position
  • It is usually non-remitting

Triggers

Types

Differential diagnosis

Other causes of daily and near daily headaches

Treatment

Prophylaxis: evidence from small case series

Prognosis

References

  1. Bigal ME, Lipton RB. The differential diagnosis of chronic daily headaches: an algorithm-based approach. J Headache Pain 2007; 8:263-272.
  2. Rozen TD. The three T's of NDPH (how clinical observations have led to improved treatment outcomes). Headache 2019; 59:1401-1406.
  3. Robbins MS, Grosberg BM, Napchan U, Crystal SC, Lipton RB. Clinical and prognostic subforms of new daily-persistent headache. Neurology 2010; 74: 1358-1364.
  4. Peng KP, Fuh JL, Yuan HK, Shia BC, Wang SJ. New daily persistent headache: should migrainous features be incorporated? Cephalalgia 2011; 31: 1561-1569.
  5. Rozen TD Triggering events and new daily persistent headache: age and gender differences and insights on pathogenesis-a clinic-based study. Headache. 2016; 56:164-173.
  6. And 5 more. Subscribe to see the full list

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