Neurosyphilis: management

Evidence-based neurology checklist on neurosyphilis: management: Indications for syphilis screening Men who have sex with men People living with HIV History of incarceration History of commercial sex work All pregnant women Cerebrospinal fluid (CSF) analysis: indications Cerebrospinal fluid (CSF)…

Indications for syphilis screening

  • Men who have sex with men
  • People living with HIV
  • History of incarceration
  • History of commercial sex work
  • All pregnant women

Cerebrospinal fluid (CSF) analysis: indications

Cerebrospinal fluid (CSF) analysis: features

Magnetic resonance imaging (MRI) brain: features

Treatment

Cerebrospinal fluid (CSF) monitoring

References

  1. Kingston M, French P, Goh B, et al. UK National guidelines on the management of syphilis 2008. Int J STD AIDS 2008; 19:729-740.
  2. Marra CM. Syphilis screening in neurology. JAMA Neurol 2016; 73:926-927.
  3. U.S. Preventive Services Task Force. Screening for syphilis infection in pregnancy: U.S. Preventive Services Task Force reaffirmation recommendation statement. Ann Intern Med 2009; 150:705-709.
  4. Hobbs E, Vera JH, Marks M, Barritt AW, Ridha BH, Lawrence D. Neurosyphilis in patients with HIV. Pract Neurol 2018; 18:211-218. 
  5. Rosa Júnior M, de Almeida Caçador T, Biasutti C, Galvão Gonçalves AM, Gonçalves Ferreira Júnior CU. Teaching NeuroImages: Skull and dural lesions in neurosyphilis. Neurology 2016; 87:e129-e130. 
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