Neurosarcoidosis associated myelopathy

Evidence-based neurology checklist on neurosarcoidosis associated myelopathy: Clinical features This is a chronically evolving myelopathy It may be the only feature of neurosarcoidosis It may present with a ‘corset-like’ lower chest pressure sensation It may present at the site of compressive…

Clinical features

  • This is a chronically evolving myelopathy
  • It may be the only feature of neurosarcoidosis
  • It may present with a ‘corset-like’ lower chest pressure sensation
  • It may present at the site of compressive cervical myelopathy
  • It may mimic non-inflammatory myelopathy

Magnetic resonance imaging (MRI): patterns

Magnetic resonance imaging (MRI): other features

Magnetic resonance imaging (MRI): enhancement patterns

Cerebrospinal fluid (CSF) features

Poor prognostic features

Treatment

Synonym

References

  1. Sakushima K, Yabe I, Nakano F, et al. Clinical features of spinal cord sarcoidosis: analysis of 17 neurosarcoidosis patients. J Neurol 2011; 258:2163-2167.
  2. Dreyer M, Vucic S, Cros DP, Chong PST. Multiple painful sensory mononeuropathies (MPSM), a novel pattern of sarcoid neuropathy. JNNP 2004; 75:1645-1652.
  3. Soni N, Bathla G, Pillenahalli Maheshwarappa R. Imaging findings in spinal sarcoidosis: a report of 18 cases and review of the current literature. Neuroradiol J 2018; doi: 10.1177/1971400918806634 (Epub ahead of print).
  4. Murphy OC, Salazar-Camelo A, Jimenez JA, et al. Clinical and MRI phenotypes of sarcoidosis-associated myelopathy. Neurol Neuroimmunol Neuroinflamm 2020; pii: e722.
  5. Kasliwal MK, Harbhajanka A, Nag S, O'Toole JE. Isolated spinal neurosarcoidosis: an enigmatic intramedullary spinal cord pathology-case report and review of the literature. J Craniovertebr Junction Spine 2013; 4:76-81.
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