Narcolepsy: differential diagnosis

Evidence-based neurology checklist on narcolepsy: differential diagnosis: Differential diagnosis of excessive sleepiness Poor night sleep Obstructive sleep apnoea (OSA) Circadian rhythm disorder Idiopathic hypersomnolence Periodic limb movements of sleep (PLMS) Depression Head injury Night-time…

Differential diagnosis of excessive sleepiness

  • Poor night sleep
  • Obstructive sleep apnoea (OSA)
  • Circadian rhythm disorder
  • Idiopathic hypersomnolence
  • Periodic limb movements of sleep (PLMS)
  • Depression
  • Head injury
  • Night-time pain
  • Hypnotics
  • Antiepileptic drugs (AEDs)
  • Syncope
  • Epilepsy

Differential diagnosis of cataplexy

References

  1. Zeman A, Britton T, Douglas N, et al. Narcolepsy and excessive daytime sleepiness. BMJ 2004; 329:724-728.
  2. Reading P. The neurological sleep clinic Part 1: the sleepy patient. ACNR 2008; 8:6-9.
  3. Plazzi G, Pizza F, Palaia V, et al. Complex movement disorders at disease onset in childhood narcolepsy with cataplexy. Brain 2011; 134:3480-3492.
  4. Stores G. Clinical diagnosis and misdiagnosis of sleep disorders. JNNP 2007; 78:1293-1297.
  5. Leschziner G. Narcolepsy: a clinical review. Pract Neurol 2014; 14:323-331.
  6. And 6 more. Subscribe to see the full list

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