Myasthenia gravis (MG): classification

Evidence-based neurology checklist on myasthenia gravis (mg): classification: Early-onset MG with acetylcholine receptor antibodies This is usually in females Age at onset is<50 years It is associated with thymic hyperplasia Late-onset MG with acetylcholine receptor antibodies MUSK associated MG…

Early-onset MG with acetylcholine receptor antibodies

  • This is usually in females
  • Age at onset is<50 years
  • It is associated with thymic hyperplasia

Late-onset MG with acetylcholine receptor antibodies

MUSK associated MG

LRP4 associated MG

Antibody negative (seronegative) MG

Thymoma associated MG

Ocular MG

Other MG types

Acronyms

References

  1. Gilhus NE, Verschuuren JJ. Myasthenia gravis: subgroup classification and therapeutic strategies. Lancet Neurol 2015; 14:1023-1036.
  2. Jayam Trouth A, Dabi A, Solieman N, Kurukumbi M, Kalyanam J. Myasthenia gravis: a review. Autoimmune Dis 2012; 2012:874680.
  3. Gilhus NE, Owe JF, Hoff JM, Romi F, Skele GO, Aarli JA. Myasthenia gravis: a review of available treatment approaches. Autoimmune Dis 2011; 10:1-6.
  4. Sieb JP. Myasthenia gravis: an update for the clinician. Clin Exp Immunol 2014; 175:408-418.
  5. Mergenthaler P, Stetefeld HR, Dohmen C, et al. Seronegative myasthenic crisis: a multicenter analysis. J Neurol 2022; 269:3904-3911. 
  6. And 2 more. Subscribe to see the full list

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