Muscle channelopathies: general features
Evidence-based neurology checklist on muscle channelopathies: general features: Myotonia This is muscle stiffness due to difficulty in relaxing muscle contractions It is tested by percussion and handgrip It is relieved by exercise and repetition: this is the warm-up phenomenon Paramyotonia…
Myotonia
- This is muscle stiffness due to difficulty in relaxing muscle contractions
- It is tested by percussion and handgrip
- It is relieved by exercise and repetition: this is the warm-up phenomenon
Paramyotonia
Episodic weakness: triggers
Other features
References
- Rakowicz W, Hanna M. Muscle ion channel diseases. ACNR 2003; 3:14-16.
- Platt D, Griggs R. Skeletal muscle channelopathies: new insights into the periodic paralyses and nondystrophic myotonias. Curr Opin Neurol 2009; 22:524-531.
- Horga A, Raja Rayan DL, Matthews E, et al. Prevalence study of genetically defined skeletal muscle channelopathies in England. Neurology 2013; 80:1472-1475.
- Spillane J, Kullmann DM, Hanna MG. Genetic neurological channelopathies: molecular genetics and clinical phenotypes. JNNP 2016; 87:37-48.
- Kullmann DM, Waxman SG. Neurological channelopathies: new insights into disease mechanisms and ion channel function. J Physiol 2010; 588:1823-1827.
