Muscle biopsy

Evidence-based neurology checklist on muscle biopsy: Indications Rapidly progressive muscle weakness Diagnosis of myopathies Asymptomatic or minimally symptomatic hyperCKaemia Vasculitic neuropathy Isolated muscle masses Choice of muscle site Pre-procedural precautions Procedural precautions…

Indications

  • Rapidly progressive muscle weakness
  • Diagnosis of myopathies
  • Asymptomatic or minimally symptomatic hyperCKaemia
  • Vasculitic neuropathy
  • Isolated muscle masses

Choice of muscle site

Pre-procedural precautions

Procedural precautions

Specimen processing

Stains used

Disease patterns

References

  1. Joyce NC, Oskarsson B, Jin LW. Muscle biopsy evaluation in neuromuscular disorders. Phys Med Rehabil Clin N Am 2012; 23:609-631.
  2. Meola G, Bugiardini E, Cardani R. Muscle biopsy. J Neurol 2012; 259:601-610.
  3. Dabby R, Sadeh M, Herman O, et al. Asymptomatic or minimally symptomatic hyperCKemia: histopathologic correlates. Isr Med Assoc J 2006; 8:110-113.
  4. Vital C, Vital A, Canron MH, et al. Combined nerve and muscle biopsy in the diagnosis of vasculitic neuropathy. A 16-year retrospective study of 202 cases. J Peripher Nerv Syst 2006; 11:20-29. 
  5. Agadi JB, Raghav G, Mahadevan A, Shankar SK. Usefulness of superficial peroneal nerve/peroneus brevis muscle biopsy in the diagnosis of vasculitic neuropathy. J Clin Neurosci 2012; 19:1392-1396. 
  6. And 5 more. Subscribe to see the full list

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