Motor neurone disease (MND): neuromuscular features
Evidence-based neurology checklist on motor neurone disease (mnd): neuromuscular features: Onset The onset is relatively abrupt Diabetes may delay the onset by 4 years Major MND subtypes Signs of muscle weakness Other neuromuscular features Tongue features Bulbar and pseudobulbar features Split…
Onset
- The onset is relatively abrupt
- Diabetes may delay the onset by 4 years
Major MND subtypes
Signs of muscle weakness
Other neuromuscular features
Tongue features
Bulbar and pseudobulbar features
Split signs
References
- Mitsumoto H. Diagnosis and progression of ALS. Neurology 1997; 48(Suppl 4):S2- S8.
- de Carvalho M, Swash M. The onset of amyotrophic lateral sclerosis. JNNP 2006; 77:388-389.
- Jawaid A, Salamone AR, Strutt AM, et al. ALS disease onset may occur later in patients with pre-morbid diabetes mellitus. Eur J Neurol 2010; 17:733-739.
- Brooks BR. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. J Neurol Sci 1994; 124(Suppl):96-107.
- Bedlack RS, Vaughan T, Wicks P, et al. How common are ALS plateaus and reversals? Neurology 2016; 86:808-812.
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