Microscopic polyangiitis (MPA): clinical features
Evidence-based neurology checklist on microscopic polyangiitis (mpa): clinical features: Pathology This is a systemic ANCA associated vasculitis (AAV) It is predominantly a pulmonary-renal syndrome It affects capillaries, venules, and arterioles It is usually MPO-ANCA positive but it may be…
Pathology
- This is a systemic ANCA associated vasculitis (AAV)
- It is predominantly a pulmonary-renal syndrome
- It affects capillaries, venules, and arterioles
- It is usually MPO-ANCA positive but it may be PR3-ANCA positive
- There are no immune complex deposits on immunofluorescence
Possible triggers
Constitutional features
Respiratory features
Renal features
Dermatological features
Neurological features: central
Neurological features: peripheral
Cardiovascular features
Gastrointestinal features
Other features
Differential diagnosis
References
- Takahashi K, Hayashi S, Ushiyama O, Sueoka N, Fukuoka M, Nagasawa K. Development of microscopic polyangiitis in patients with chronic airway disease. Lung 2005; 183:273-281.
- Chung SA, Seo P. Microscopic polyangiitis. Rheum Dis Clin North Am 2010; 36:545-558.
- Eleftheriou D, Katsenos S, Zorbas S, Griveas I, Psathakis K. Pulmonary fibrosis presenting as an early manifestation of microscopic polyangiitis. Monaldi Arch Chest Dis 2012; 77:141-144.
- García-Nava M, Mateos-Toledo H, Guevara-Canseco APG, Infante-González CE, Reyes-Nava DA, Estrada-Castro E. Early interstitial lung disease in microscopic polyangiitis: case report and literature review. Reumatol Clin 2018; 14:106-108.
- Kallenberg CG. The diagnosis and classification of microscopic polyangiitis. J Autoimmun 2014; 48-49:90-93.
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