MERRF: treatment

Evidence-based neurology checklist on merrf: treatment: Mitochondrial treatments Coenzyme Q10 Vitamin B complex L-carnitine Treatment of myoclonus Treatment of seizures Drugs to avoid Acronym

Mitochondrial treatments

  • Coenzyme Q10
  • Vitamin B complex
  • L-carnitine

Treatment of myoclonus

Treatment of seizures

Drugs to avoid

Acronym

References

  1. Rahman S, Hanna MG. Diagnosis and therapy in neuromuscular disorders: diagnosis and new treatments in mitochondrial diseases. JNNP 2009; 80:943-953.
  2. Lorenzoni PJ, Scola RH, Kay CS, Silvado CE, Werneck LC. When should MERRF) myoclonus epilepsy associated with ragged-red fibers) be the diagnosis? Arq Neuropsiquiatr 2014; 72:803-811.
  3. Finsterer J, Zarrouk-Mahjoub S. Management of epilepsy in MERRF syndrome. Seizure 2017; 50:166-170.
  4. Finsterer J. A review of the advances in the medical management of epilepsy associated with myoclonic epilepsy with ragged-red fibers (MERRF) syndrome. Cureus 2025; 17:e82875.

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