Medication overuse headache (MOH): clinical features

Evidence-based neurology checklist on medication overuse headache (moh): clinical features: Diagnostic criteria Headache occurs on ≥15 days a month on Paracetamol, Aspirin or NSAIDs Headache occurs on ≥10 days a month for Opiates, Triptans or Ergotamine Regular analgesic use on ≥2 days a week for…

Diagnostic criteria

  • Headache occurs on ≥15 days a month on Paracetamol, Aspirin or NSAIDs
  • Headache occurs on ≥10 days a month for Opiates, Triptans or Ergotamine
  • Regular analgesic use on ≥2 days a week for ≥3 months
  • Headache develops or worsens during drug treatment of a primary headache
  • Headache resolves or reverts within 2 months of drug discontinuation

Individual risk factors

Medical risk factors

Clinical features

Differential diagnosis

Acronym

References

  1. Evers S, Jensen R. Treatment of medication overuse headache-guideline of the EFNS headache panel. Eur J Neurol 2011; 18:1115-1121.
  2. Wakerley BR. Medication-overuse headache. Pract Neurol 2019; 19:399-403.
  3. Hagen K, Linde M, Steiner TJ, Stovner LJ, Zwart JA. Risk factors for medication-overuse headache: an 11-year follow-up study. The Nord-Trondelag Health Studies. Pain 2012; 153:56-61.
  4. Diener HC, Dodick D, Evers S, et al. Pathophysiology, prevention, and treatment of medication overuse headache. Lancet Neurol 2019; pii: S1474-4422(19)30146-2 (Epub ahead of print).
  5. Diener HC, Antonaci F, Braschinsky M, et al. European Academy of Neurology guideline on the management of medication-overuse headache. Eur J Neurol 2020; 27:1102-1116. 
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