Malignant brain edema (MBE)

Evidence-based neurology checklist on malignant brain edema (mbe): Clinical features Cerebral oedema with mass effect With malignant cerebral artery (MCA) infarctions Predictors Treatment

Clinical features

  • Cerebral oedema with mass effect
  • With malignant cerebral artery (MCA) infarctions

Predictors

Treatment

References

  1. Treadwell SD, Thanvi B. Malignant middle cerebral artery (MCA) infarction: pathophysiology, diagnosis and management. Postgrad Med J 2010; 86:235-242.
  2. Jo K, Bajgur SS, Kim H, Choi HA, Huh PW, Lee K. A simple prediction score system for malignant brain edema progression in large hemispheric infarction. PLoS One 2017; 12:e0171425.
  3. Mlynash M, Lansberg MG, De Silva DA, et al. Redefining the definition of the malignant profile: insights from the DEFUSE-EPITHET polled data set. Stroke 2011; 42:1270-1275.
  4. Streib CD, Hartman LM, Molyneaux BJ. Early decompressive craniectomy for malignant cerebral infarction: Meta-analysis and clinical decision algorithm. Neurol Clin Pract 2016; 6:433-443. 
  5. van der Worp HB, Hofmeijer J, Jüttler E, et al. European Stroke Organisation (ESO) guidelines on the management of space-occupying brain infarction. Eur Stroke J 2021; 6:XC-CX. 
  6. And 2 more. Subscribe to see the full list

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