Madras motor neuron disease (MMND)

Evidence-based neurology checklist on madras motor neuron disease (mmnd): Epidemiologic features India: this has the most cases Korea Turkey China Pakistan Thailand Demographic features Clinical features of MMND Differential diagnosis Magnetic resonance imaging (MRI) brain Pathological features…

Epidemiologic features

  • India: this has the most cases
  • Korea
  • Turkey
  • China
  • Pakistan
  • Thailand

Demographic features

Clinical features of MMND

Differential diagnosis

Magnetic resonance imaging (MRI) brain

Pathological features

Treatment

References

  1. Gourie-Devi M, Suresh TG. Madras pattern of motor neuron disease in South India. JNNP 1988; 51:773-777.
  2. Gourie-Devi M, Maheshwari S, Panda AK, Bala K. Chin fasciculations in Madras motor neuron disease: a new clinical feature. Neurol India 2013; 61:653-655.
  3. Nalini A, Thennarasu K, Yamini BK, Shivashankar D, Krishna N. Madras motor neuron disease (MMND): clinical description and survival pattern of 116 patients from Southern India seen over 36 years (1971-2007). J Neurol Sci 2008; 269:65-73.
  4. Long L, Cai X, Liu J, et al. A Madras motor neuron disease patient with cerebellar atrophy: a new clinical feature. Front Neurosci 2018; 12:722. 
  5. Nalini A, Pandraud A, Mok K, Houlden H. Madras motor neuron disease (MMND) is distinct from the riboflavin transporter genetic defects that cause Brown-Vialetto-Van Laere syndrome. J Neurol Sci 2013; 334:119-122.
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