Lithium toxicity: risk factors

Evidence-based neurology checklist on lithium toxicity: risk factors: Medical risk factors Older age Physical illness: with diarrhoea and vomiting Renal impairment Schizophrenia Rapid Stroke Bariatric surgery Correction of hyponatraemia Drug-interaction risk factors

Medical risk factors

  • Older age
  • Physical illness: with diarrhoea and vomiting
  • Renal impairment
  • Schizophrenia
  • Rapid Stroke
  • Bariatric surgery
  • Correction of hyponatraemia

Drug-interaction risk factors

References

  1. Newman PK, Saunders M. Lithium neurotoxicity. Postgrad Med J 1979; 55:701-703.
  2. Suraya Y, Yoong KY. Lithium neurotoxicity. Med J Malaysia 2001; 56:378-381.
  3. Moskowitz AS, Altshuler L. Increased sensitivity to lithium-induced neurotoxicity after stroke: a case report. J Clin Psychopharmacol 1991; 11:272-273.
  4. Musfeldt D, Levinson A, Nykiel J, Carino G. Lithium toxicity after Roux-en-Y bariatric surgery. BMJ Case Rep 2016; pii: bcr2015214056.
  5. Roy M, Stip E, Black D, Lew V, Langlois R. Cerebellar degeneration following acute lithium intoxication. Rev Neurol (Paris) 1998; 154:546-548.
  6. And 9 more. Subscribe to see the full list

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