Leprosy associated neuropathy

Evidence-based neurology checklist on leprosy associated neuropathy: Mononeuritis multiplex This is the most common presentation Overlying skin lesions increase the risk It is typically a small fiber neuropathy The upper limbs are more frequently affected Autonomic involvement may be prominent…

Mononeuritis multiplex

  • This is the most common presentation
  • Overlying skin lesions increase the risk
  • It is typically a small fiber neuropathy
  • The upper limbs are more frequently affected
  • Autonomic involvement may be prominent

Other neuropathy types

Associated clinical features

Differential diagnosis

Nerve conduction studies (NCS)

Other investigations

References

  1. Nascimento OJ. Leprosy neuropathy: clinical presentations. Arq Neuropsiquiatr 2013; 71:661-666.
  2. Ooi WW, Srinivasan J. Leprosy and the peripheral nervous system: basic and clinical aspects. Muscle Nerve 2004; 30:393-409.
  3. Galtrey CM, Modarres H, Jaunmuktane Z, et al. Leprosy in a patient infected with HIV. Pract Neurol 2017; 17:135-139.
  4. van Brakel WH, Nicholls PG, Das L, Barkataki P, et al. The INFIR Cohort Study: investigating prediction, detection and pathogenesis of neuropathy and reactions in leprosy. Methods and baseline results of a cohort of multibacillary leprosy patients in north India. Lepr Rev 2005; 76:14-34.
  5. Cabalar M, Yayla V, Ulutas S, Senadim S, Oktar AC. The clinical & neurophysiological study of leprosy. Pak J Med Sci 2014; 30:501-506.
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