Langerhans cell histiocytosis (LCH): treatment

Evidence-based neurology checklist on langerhans cell histiocytosis (lch): treatment: Treatment of skin lesions Topical steroids Topical tacrolimus Topical nitrogen mustard Topical PUVA Oral methotrexate Oral hydroxyurea Thalidomide Treatment of single organ lung lesions Treatment of multifocal…

Treatment of skin lesions

  • Topical steroids
  • Topical tacrolimus
  • Topical nitrogen mustard
  • Topical PUVA
  • Oral methotrexate
  • Oral hydroxyurea
  • Thalidomide

Treatment of single organ lung lesions

Treatment of multifocal bone lesions

Treatment of multifocal skin lesions

Treatment of multi-organ disease

Treatment of neurodegenerative symptoms

Other treatments

Investigational treatments

Treatments to avoid

Synonym

References

  1. Satter EK, High WA. Langerhans cell histiocytosis: a review of the current recommendations of the Histiocyte Society. Pediatr Dermatol 2008; 25:291-295.
  2. Leung AKC, Lam JM, Leong KF. Childhood Langerhans cell histiocytosis: a disease with many faces. World J Pediatr 2019; 15:536-545.
  3. Girschikofsky M, Arico M, Castillo D, et al. Management of adult patients with Langerhans cell histiocytosis: recommendations from an expert panel on behalf of Euro-Histio-Net.Orphanet J Rare Dis 2013; 8:72.
  4. Goyal G, Tazi A, Go RS, et al. International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults. Blood 2022; 139:2601-2621.
  5. Donadieu J, Chalard F, Jeziorski E. Medical management of Langerhans cell histiocytosis from diagnosis to treatment. Expert Opin Pharmacother 2012; 13:1309-1322.

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