Juvenile myasthenia gravis (JMG): clinical features

Evidence-based neurology checklist on juvenile myasthenia gravis (jmg): clinical features: Clinical presentation This is MG presenting before the age of 18 years The clinical presentation is similar to adult onset MG The onset is ocular in about 60% of cases Thymic abnormalities Antibody profile…

Clinical presentation

  • This is MG presenting before the age of 18 years
  • The clinical presentation is similar to adult onset MG
  • The onset is ocular in about 60% of cases

Thymic abnormalities

Antibody profile

Prognosis

References

  1. Barraud C, Desguerre I, Barnerias C, Gitiaux C, Boulay C, Chabrol B. Clinical features and evolution of juvenile myasthenia gravis in a French cohort. Muscle Nerve 2018; 57:603-609.
  2. O'Connell K, Ramdas S, Palace J. Management of juvenile myasthenia gravis. Front Neurol 2020; 11:743. 
  3. Lin Y, Kuang Q, Li H, Liang B, Lu J, Jiang Q, Yang X. Outcome and clinical features in juvenile myasthenia gravis: A systematic review and meta-analysis. Front Neurol 2023; 14:1119294.
  4. Castro D, Derisavifard S, Anderson M, Greene M, Iannaccone S. Juvenile myasthenia gravis: a twenty-year experience. J Clin Neuromuscul Dis 2013; 14:95-102.
  5. Arroyo HA, Torres AR. Spontaneous remission in juvenile myasthenia gravis: A cohort of 13 cases and review of the literature. Neuromuscul Disord 2022; 32:213-219.

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