Insomnia: drug treatments

Evidence-based neurology checklist on insomnia: drug treatments: Indication for drug treatments Failure of cognitive behaviour therapy (CBT) Drug treatments indicated for short-term use: ≤4 weeks Benzodiazepine receptor agonists: Z drugs Sedating antidepressants: if there is co-existing mood…

Indication for drug treatments

  • Failure of cognitive behaviour therapy (CBT)

Drug treatments indicated for short-term use: ≤4 weeks

Benzodiazepine receptor agonists: Z drugs

Sedating antidepressants: if there is co-existing mood disorder

Dual orexin receptor antagonists (DORA)

Other drug treatments

Treatments not recommended

Synonym

References

  1. Schutte-Rodin S, Broch L, Buysse D, Dorsey C, Sateia M. Clinical guideline for the evaluation and management of chronic insomnia in adults. J Clin Sleep Med 2008; 4:487-504.
  2. Wilson SJ, Nutt DJ, Argyropoulos SV, et al. British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. J Psychopharmacol 2010; 24:1577-1600.
  3. Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomnia. NICE technology appraisal guidance [TA77]. April 2004.
  4. Riemann D, Baglioni C, Bassetti C, et al. European guideline for the diagnosis and treatment of insomnia. J Sleep Res 2017; 26:675-700. 
  5. Sateia MJ, Buysse DJ, Krystal AD, Neubauer DN, Heald JL. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med 2017; 13:307-349. 
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