Inclusion body myositis (IBM): differential diagnosis
Evidence-based neurology checklist on inclusion body myositis (ibm): differential diagnosis: Motor neurone disease (MND) Dysphagia occurs without dysarthria in 40% of IBM cases Cramps are unusual in IBM unlike in MND Visible fasciculations are unusual in IBM Definite upper motor neurone signs are…
Motor neurone disease (MND)
- Dysphagia occurs without dysarthria in 40% of IBM cases
- Cramps are unusual in IBM unlike in MND
- Visible fasciculations are unusual in IBM
- Definite upper motor neurone signs are unusual in IBM
Other clinical differentials: causes of prominent finger flexor weakness
Histopathological differentials
References
- Dabby R, Lange DJ, Trojaborg W, et al. Inclusion body myositis mimicking motor neuron disease. Arch Neurol 2001; 58:1253-1256.
- Nicolau S, Liewluck T, Milone M. Myopathies with finger flexor weakness: Not only inclusion-body myositis. Muscle Nerve 2020; 62:445-454.
- Miyazaki M, Mori-Yoshimura M, Yamamoto T, et al. Chronic sarcoid myopathy mimicking sporadic inclusion body myositis. Clin Neurol Neurosurg 2019; 182:84-86.
- Lavian M, Goyal N, Mozaffar T. Sporadic inclusion body myositis misdiagnosed as idiopathic granulomatous myositis. Neuromuscul Disord 2016; 26:741-743.
- Larue S, Maisonobe T, Benveniste O, et al. Distal muscle involvement in granulomatous myositis can mimic inclusion body myositis. J Neurol Neurosurg Psychiatry 2011; 82:674-677.
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