Idiopathic intracranial hypertension (IIH): headache-specific treatments

Acute treatment of migraine-type headache

• Triptans
• NSAIDs: especially Naproxen and Ketoprofen: avoid Naproxen sodium
• Paracetamol
• Pro-kinetic anti-emetic drugs

Preventative treatment of migraine-type headache

Preventative treatment of migraine-type headache with risk of weight gain

Treatment of tension-type headaches

Headache drugs to avoid: risk of weight gain

Acronym

References

1. Friedman DI. Headaches in idiopathic intracranial hypertension. J Neuroophthalmol 2019; 39:82-93.
2. Mollan SP, Hoffmann J, Sinclair AJ. Advances in the understanding of headache in idiopathic intracranial hypertension. Curr Opin Neurol 2019; 32:92-98.
3. Yiangou A, Mitchell JL, Fisher C, et al. Erenumab for headaches in idiopathic intracranial hypertension: a prospective open-label evaluation. Headache 2021; 61:157-169. 
4. Yiangou A, Mitchell JL, Vijay V, et al. Calcitonin gene related peptide monoclonal antibody treats headache in patients with active idiopathic intracranial hypertension. J Headache Pain 2020; 21:116.

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