Hypothalamic hamartoma: management

Evidence-based neurology checklist on hypothalamic hamartoma: management: Genetic mutations GLIR OFD1 PRKACA TKN2 possibly Electroencephalogram (EEG) Magnetic resonance imaging (MRI) brain Drug treatment Surgical ablation

Genetic mutations

  • GLIR
  • OFD1
  • PRKACA
  • TKN2 possibly

Electroencephalogram (EEG)

Magnetic resonance imaging (MRI) brain

Drug treatment

Surgical ablation

References

  1. Striano S, Striano P. Clinical features and evolution of the gelastic seizures-hypothalamic hamartoma syndrome. Epilepsia 2017; 58(Suppl 2):12-15. 
  2. Helen Cross J, Spoudeas H. Medical management and antiepileptic drugs in hypothalamic hamartoma. Epilepsia 2017; (58 Suppl 2):16-21. 
  3. Sami L, Chipaux M, Ferrand-Sorbets S, et al. Genetic insights into hypothalamic hamartoma: unraveling somatic variants. Neurol Genet 2024; 10:e200180.
  4. Striano S, Striano P, Sarappa C, Boccella P. The clinical spectrum and natural history of gelastic epilepsy-hypothalamic hamartoma syndrome. Seizure 2005; 14:232-239.
  5. Dericioglu N, Cataltepe O, Tezel GG, Saygi S. Gelastic seizures due to right temporal cortical dysplasia. Epileptic Disord 2005; 7:137-141.
  6. And 4 more. Subscribe to see the full list

Related checklists

Loading...